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KMID : 1023920170190030061
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Journal of the Korean Academy of Kinesiology
2017 Volume.19 No. 3 p.61 ~ p.70
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Associations of Sarcopenia with Rheumatoid Arthritis and Osteoarthritis in Korean Adults : the Korea National Health and Nutrition Examination Survey 2008-2011
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Yoon Jeong-Gyo
Kim Jung-Hoon
Choi Yoon-Hyeong
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Abstract
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PURPOSE: This study aimed to investigate the associations of sarcopenia with rheumatoid arthritis and osteoarthritis in the general population of Korean adults.
METHODS: We analyzed the data for 11,466 adults aged ≥40 years from the Korea National Health and Nutrition Examination Survey 2008-2011. Dual-energy X-ray absorptiometry was used to measure the skeletal muscle mass. Sarcopenia was defined when the appendicular skeletal muscle index was less than the sex-specific average minus the two standard deviations in the young reference group(age, 20-39 years). Survey logistic regression analysis was used to assess the association of sarcopenia with rheumatoid arthritis and osteoarthritis.
RESULTS: Sarcopenia status was dose-dependently associated with a higher risk of rheumatoid arthritis, after adjustment for potential confounders(p-trend=.002, odds ratio [OR], 2.14; 95% confidence interval [CI], 1.13, 4.05 in sarcopenia group vs. high muscle mass group). However, a higher risk of osteoarthritis was observed in pre-sarcopenia group compared with the high muscle mass group(OR, 1.45; 95% CI, 1.03, 2.05), but not in sarcopenia group.
CONCLUSIONS: We found that sarcopenia status was associated with rheumatoid arthritis, and pre-sarcopenia status was associated with osteoarthritis. Our findings suggest that maintaining a skeletal muscle could be beneficial in preventing musculoskeletal disorders, including rheumatoid arthritis and osteoarthritis.
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KEYWORD
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sarcopenia, skeletal muscle mass, rheumatoid arthritis, osteoarthritis, KNHANES
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